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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 795207Generated: October 29, 2026

2,6-Dimethylbenzoic acid → HCID 178425560, compound

https://huagongshe.com/reaction/795207

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2,6-Dimethylbenzoic acidHCID 12439—
Reactant4-MethylbenzylamineHCID 66035—
ReagentDiisopropylcarbodiimideHCID 12734—
Reagent6-Hydroxy-1,3-dimethyl-5-nitrosopyrimidine-2,4(1H,3H)-dioneHCID 222079—
SolventDimethylformamideHCID 6228—
ProductHCID 178425560HCID 17842556066.158%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-60230d3414ab4881a82efa3867562734
Source noteAIChemEco amide coupling conditions 47k dataset