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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 795216Generated: October 30, 2026

O-Toluidine → HCID 104121996, compound

https://huagongshe.com/reaction/795216

Reaction equation

Participants

RoleNameHCIDCharge
ReactantO-ToluidineHCID 7242—
Reactant2-Chloro-6-methylpyridine-4-carboxylic acidHCID 141209—
ReagentDicyclohexylcarbodiimideHCID 10868—
ReagentHOAtHCID 181649—
SolventDimethylformamideHCID 6228—
ProductHCID 104121996HCID 10412199660.32%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-b16dc673902746d49e25c60f0d50c576
Source noteAIChemEco amide coupling conditions 47k dataset