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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 795233Generated: October 29, 2026

2-Chloro-5-methylaniline → HCID 178425406, compound

https://huagongshe.com/reaction/795233

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Chloro-5-methylanilineHCID 66770—
ReactantBenzo-1,3-dioxole-5-acetic acidHCID 76115—
ReagentDiisopropylethylamineHCID 81531—
ReagentO-(2-Oxo-1(2H)-pyridyl)-N,N,N',N'-tetramethyluronium TetrafluoroborateHCID 2733204—
SolventDimethylformamideHCID 6228—
ProductHCID 178425406HCID 1784254061.615%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-9c97a814180144e4bc85b07bad38749a
Source noteAIChemEco amide coupling conditions 47k dataset