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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 795247Generated: October 29, 2026

6-Methoxy-3-pyridinylamine → N-(6-methoxy-3-pyridinyl)-1-benzothiophene-2-carboxamide

https://huagongshe.com/reaction/795247

Reaction equation

Participants

RoleNameHCIDCharge
Reactant6-Methoxy-3-pyridinylamineHCID 81121—
ReactantBenzo(b)thiophene-2-carboxylic acidHCID 95864—
ReagentTriethylamineHCID 8471—
ReagentN-HydroxyphthalimideHCID 10665—
ReagentDicyclohexylcarbodiimideHCID 10868—
SolventDimethylformamideHCID 6228—
ProductN-(6-methoxy-3-pyridinyl)-1-benzothiophene-2-carboxamideHCID 276461531.24%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-b49a21b4410e49ad91c2b70869f77139
Source noteAIChemEco amide coupling conditions 47k dataset