6-(4-biphenylyl)-4-carboxy-2-isobutyl-2H-pyridazin-3-one → 6-(4-biphenylyl)-4-hydroxymethyl-2-isobutyl-2H-pyridazin-3-one

HRID 7953Notes

Reaction equation

HRID 7953 reaction equation
C(OC(N1CCN(C2C(=O)N(CC(C)C)N=C(C3C=CC(C(F)(F)F)=CC=3)C=2C)CC1)=O)(C)(C)C.[C:36]1([C:56]2[CH:61]=[CH:60][CH:59]=[CH:58][CH:57]=2)[CH:41]=[CH:40][C:39]([C:42]2[CH:43]=[C:44]([C:53](O)=[O:54])[C:45](=[O:52])[N:46]([CH2:48][CH:49]([CH3:51])[CH3:50])[N:47]=2)=[CH:38][CH:37]=1>>[C:36]1([C:56]2[CH:57]=[CH:58][CH:59]=[CH:60][CH:61]=2)[CH:37]=[CH:38][C:39]([C:42]2[CH:43]=[C:44]([CH2:53][OH:54])[C:45](=[O:52])[N:46]([CH2:48][CH:49]([CH3:50])[CH3:51])[N:47]=2)=[CH:40][CH:41]=1

Participants

3

Reactant 2

HCID 219915196-(4-biphenylyl)-4-carboxy-2-isobutyl-2H-pyridazin-3-oneHCID 67213081HCID 67213081, compound

Product 1

HCID 219915526-(4-biphenylyl)-4-hydroxymethyl-2-isobutyl-2H-pyridazin-3-one

Procedure

Following the procedure of Example 1 (8), 6-(4-biphenylyl)-4-carboxy-2-isobutyl-2H-pyridazin-3-one was reacted to yield the title compound as a while solid (yield: 15.6%).

Workup

  1. customwas reacted

Sources & evidence

ORD record
ord-f8f54937e925455ca895367bff749d2c
Source dataset
uspto-grants-2006_08
Patent number
US07087606B2

Reaction notes

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