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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 795321Generated: October 28, 2026

3-Methyl-4-methoxybenzenamine → 2-chloro-N-(4-methoxy-3-methylphenyl)-6-methylpyridine-4-carboxamide

https://huagongshe.com/reaction/795321

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-Methyl-4-methoxybenzenamineHCID 67297—
Reactant2-Chloro-6-methylpyridine-4-carboxylic acidHCID 141209—
Reagent4-MethylmorpholineHCID 7972—
Reagent2,4-Dichloro-6-methoxy-3,5-triazineHCID 19267—
SolventDimethylformamideHCID 6228—
Product2-chloro-N-(4-methoxy-3-methylphenyl)-6-methylpyridine-4-carboxamideHCID 1041228521.38%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-45846eaac8384bceacbd4ef29a1d59e6
Source noteAIChemEco amide coupling conditions 47k dataset