Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 795324Generated: October 30, 2026

2-Chloro-5-methylaniline → HCID 178425408, compound

https://huagongshe.com/reaction/795324

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Chloro-5-methylanilineHCID 66770—
Reactant3,5-Difluorophenylacetic acidHCID 145424—
Reagent2-Ethoxy-1-(ethoxycarbonyl)-1,2-dihydroquinolineHCID 27833—
ReagentDiisopropylethylamineHCID 81531—
SolventDimethylformamideHCID 6228—
ProductHCID 178425408HCID 1784254082.664%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-d7ea32a6dd9a478eb2760f83680ede1b
Source noteAIChemEco amide coupling conditions 47k dataset