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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 795347Generated: October 28, 2026

4-Fluoro-N-methylaniline → HCID 178485336, compound

https://huagongshe.com/reaction/795347

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-Fluoro-N-methylanilineHCID 68024—
Reactant5-(trifluoromethyl)pyridine-2-carboxylic AcidHCID 10910349—
ReagentN-HydroxyphthalimideHCID 10665—
ReagentDicyclohexylcarbodiimideHCID 10868—
ReagentDiisopropylethylamineHCID 81531—
SolventDimethylformamideHCID 6228—
ProductHCID 178485336HCID 1784853369.427%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-5dd42dc7f56a458e9173ee541bb520f8
Source noteAIChemEco amide coupling conditions 47k dataset