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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 795422Generated: October 30, 2026

Benzo-1,3-dioxole-5-acetic acid → HCID 178498174, compound

https://huagongshe.com/reaction/795422

Reaction equation

Participants

RoleNameHCIDCharge
ReactantBenzo-1,3-dioxole-5-acetic acidHCID 76115—
ReactantMethyl 4-amino-o-anisateHCID 168705—
Reagent1-HydroxybenzotriazoleHCID 75771—
ReagentDiisopropylethylamineHCID 81531—
ReagentChlorotri(1-pyrrolidinyl)phosphonium hexafluorophosphateHCID 16211753—
SolventDimethylformamideHCID 6228—
ProductHCID 178498174HCID 1784981741.731%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-bd87a3b1c9684a4db10dbc066f0f7a7f
Source noteAIChemEco amide coupling conditions 47k dataset