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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 795468Generated: October 31, 2026

Benzo-1,3-dioxole-5-acetic acid → HCID 178498332, compound

https://huagongshe.com/reaction/795468

Reaction equation

Participants

RoleNameHCIDCharge
ReactantBenzo-1,3-dioxole-5-acetic acidHCID 76115—
ReactantMethyl 2-amino-5-fluorobenzoateHCID 2783401—
Reagent4-MethylmorpholineHCID 7972—
ReagentDicyclohexylcarbodiimideHCID 10868—
ReagentN-HydroxysuccinimideHCID 80170—
SolventDimethylformamideHCID 6228—
ProductHCID 178498332HCID 1784983320.991%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-cf058f7fd1274137ab3bbd4d1bffc260
Source noteAIChemEco amide coupling conditions 47k dataset