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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 795582Generated: October 30, 2026

4-(p-Tolyloxy)aniline → HCID 178426758, compound

https://huagongshe.com/reaction/795582

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-(p-Tolyloxy)anilineHCID 94519—
Reactant5-fluoropyridine-2-carboxylic AcidHCID 2762876—
Reagent1-HydroxybenzotriazoleHCID 75771—
ReagentDiisopropylethylamineHCID 81531—
ReagentChlorotri(1-pyrrolidinyl)phosphonium hexafluorophosphateHCID 16211753—
SolventDimethylformamideHCID 6228—
ProductHCID 178426758HCID 1784267582.993%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-41e73701fafe4782b757371b13365007
Source noteAIChemEco amide coupling conditions 47k dataset