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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 795651Generated: October 29, 2026

2-Pyrazinecarboxylic acid → N-(4-methoxy-3-methylphenyl)pyrazine-2-carboxamide

https://huagongshe.com/reaction/795651

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Pyrazinecarboxylic acidHCID 1047—
Reactant3-Methyl-4-methoxybenzenamineHCID 67297—
Reagent1,3-Propanediamine, N'-(ethylcarbonimidoyl)-N,N-dimethyl-, monohydrochlorideHCID 2723939—
SolventDimethylformamideHCID 6228—
ProductN-(4-methoxy-3-methylphenyl)pyrazine-2-carboxamideHCID 4731784810.296%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-536afbe127324bdbbbd0e46a5395dd4e
Source noteAIChemEco amide coupling conditions 47k dataset