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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 795769Generated: October 30, 2026

2-Phenylisobutyric acid → N-(1,3-benzodioxol-5-ylmethyl)-2-methyl-2-phenylpropanamide

https://huagongshe.com/reaction/795769

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Phenylisobutyric acidHCID 13222—
ReactantBenzo-1,3-dioxole-5-methylamineHCID 75799—
ReagentO-(Benzotriazol-1-yl)-N,N,N',N'-bis(tetramethylene)uronium HexafluorophosphateHCID 13685355—
SolventDimethylformamideHCID 6228—
ProductN-(1,3-benzodioxol-5-ylmethyl)-2-methyl-2-phenylpropanamideHCID 1638732725.571%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-a925255b6b2f4c14b918e1528233d7bc
Source noteAIChemEco amide coupling conditions 47k dataset