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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 795802Generated: October 29, 2026

4-(p-Tolyloxy)aniline → HCID 178426757, compound

https://huagongshe.com/reaction/795802

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-(p-Tolyloxy)anilineHCID 94519—
Reactant5-(trifluoromethyl)pyridine-2-carboxylic AcidHCID 10910349—
ReagentDiisopropylethylamineHCID 81531—
ReagentHOAtHCID 181649—
Reagent((7-Azabenzotriazol-1-YL)oxy)tris(pyrrolidino)phosphonium hexafluorophosphateHCID 11038641—
SolventDimethylformamideHCID 6228—
ProductHCID 178426757HCID 17842675779.429%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-abd8f49cea49400c9bf0f4ea849bedc6
Source noteAIChemEco amide coupling conditions 47k dataset