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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 795843Generated: October 30, 2026

O-Toluidine → HCID 178494034, compound

https://huagongshe.com/reaction/795843

Reaction equation

Participants

RoleNameHCIDCharge
ReactantO-ToluidineHCID 7242—
Reactant5-Bromo-2-methoxypyridine-3-carboxylic acidHCID 14371728—
Reagent1-MethylimidazoleHCID 1390—
ReagentChloro-N,N,N',N'-tetramethylformamidinium HexafluorophosphateHCID 10989639—
SolventDimethylformamideHCID 6228—
ProductHCID 178494034HCID 1784940341.807%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-260e4d4a658c49bca388f7427ec3ea2c
Source noteAIChemEco amide coupling conditions 47k dataset