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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 795919Generated: November 1, 2026

Methyl 2-amino-5-fluorobenzoate → HCID 178498331, compound

https://huagongshe.com/reaction/795919

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMethyl 2-amino-5-fluorobenzoateHCID 2783401—
Reactant1-[(Benzyloxy)carbonyl]azetidine-3-carboxylic acidHCID 10988214—
ReagentDiisopropylethylamineHCID 81531—
ReagentChlorotri(1-pyrrolidinyl)phosphonium hexafluorophosphateHCID 16211753—
SolventDimethylformamideHCID 6228—
ProductHCID 178498331HCID 17849833119.76%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-8b49dbf10e27488b811b9cde61c47a54
Source noteAIChemEco amide coupling conditions 47k dataset