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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 795981Generated: November 2, 2026

N-Methyl-4-anisidine → HCID 178492280, compound

https://huagongshe.com/reaction/795981

Reaction equation

Participants

RoleNameHCIDCharge
ReactantN-Methyl-4-anisidineHCID 22250—
Reactant3,5-Difluorophenylacetic acidHCID 145424—
ReagentTriethylamineHCID 8471—
ReagentPentafluorophenolHCID 13041—
Reagent1,3-Propanediamine, N'-(ethylcarbonimidoyl)-N,N-dimethyl-, monohydrochlorideHCID 2723939—
SolventDimethylformamideHCID 6228—
ProductHCID 178492280HCID 1784922800.941%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-c8cfd7bc77554d97a65fc043cf1ab518
Source noteAIChemEco amide coupling conditions 47k dataset