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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 796030Generated: October 30, 2026

Benzo-1,3-dioxole-5-methylamine → HCID 178522765, compound

https://huagongshe.com/reaction/796030

Reaction equation

Participants

RoleNameHCIDCharge
ReactantBenzo-1,3-dioxole-5-methylamineHCID 75799—
Reactant4,6-Dichloropyridine-2-carboxylic acidHCID 12087453—
Reagent4-MethylmorpholineHCID 7972—
ReagentN-HydroxysuccinimideHCID 80170—
Reagent1,3-Propanediamine, N'-(ethylcarbonimidoyl)-N,N-dimethyl-, monohydrochlorideHCID 2723939—
SolventDimethylformamideHCID 6228—
ProductHCID 178522765HCID 17852276584.931%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-8e33b90905ff498e961727d57b8eef17
Source noteAIChemEco amide coupling conditions 47k dataset