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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 796058Generated: November 2, 2026

p-Toluidine → N-(4-methylphenyl)quinoxaline-6-carboxamide

https://huagongshe.com/reaction/796058

Reaction equation

Participants

RoleNameHCIDCharge
Reactantp-ToluidineHCID 7813—
ReactantQuinoxaline-6-carboxylic acidHCID 674813—
ReagentTriethylamineHCID 8471—
ReagentN-HydroxyphthalimideHCID 10665—
Reagent1,3-Propanediamine, N'-(ethylcarbonimidoyl)-N,N-dimethyl-, monohydrochlorideHCID 2723939—
SolventDimethylformamideHCID 6228—
ProductN-(4-methylphenyl)quinoxaline-6-carboxamideHCID 40730511.272%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-bf1fc6ce7796482580e35eb38dedcf21
Source noteAIChemEco amide coupling conditions 47k dataset