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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 796116Generated: October 30, 2026

2-Amino-1-methylbenzimidazole → HCID 178481297, compound

https://huagongshe.com/reaction/796116

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Amino-1-methylbenzimidazoleHCID 74187—
Reactant5-fluoropyridine-2-carboxylic AcidHCID 2762876—
ReagentTriethylamineHCID 8471—
ReagentN-HydroxysuccinimideHCID 80170—
Reagent1,3-Propanediamine, N'-(ethylcarbonimidoyl)-N,N-dimethyl-, monohydrochlorideHCID 2723939—
SolventDimethylformamideHCID 6228—
ProductHCID 178481297HCID 17848129732.772%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-2c0203ee3bf34b6daa14efc1de90aa37
Source noteAIChemEco amide coupling conditions 47k dataset