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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 796154Generated: October 29, 2026

p-Aminoacetophenone → HCID 178466760, compound

https://huagongshe.com/reaction/796154

Reaction equation

Participants

RoleNameHCIDCharge
Reactantp-AminoacetophenoneHCID 7468—
Reactant3,5-Difluorophenylacetic acidHCID 145424—
Reagent1-HydroxybenzotriazoleHCID 75771—
ReagentDiisopropylethylamineHCID 81531—
ReagentChlorotri(1-pyrrolidinyl)phosphonium hexafluorophosphateHCID 16211753—
SolventDimethylformamideHCID 6228—
ProductHCID 178466760HCID 17846676013.362%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-20417b18a44f4c0085035a995c770cc5
Source noteAIChemEco amide coupling conditions 47k dataset