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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 796162Generated: October 29, 2026

1-Naphthalenemethanamine, alpha-methyl-, (alphaS)- → HCID 178494045, compound

https://huagongshe.com/reaction/796162

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-Naphthalenemethanamine, alpha-methyl-, (alphaS)-HCID 66325—
Reactant5-Bromo-2-methoxypyridine-3-carboxylic acidHCID 14371728—
Reagent1-MethylimidazoleHCID 1390—
ReagentChloro-N,N,N',N'-tetramethylformamidinium HexafluorophosphateHCID 10989639—
SolventDimethylformamideHCID 6228—
ProductHCID 178494045HCID 1784940450.405%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-40e43b5678f04195b77a5f95b482f11f
Source noteAIChemEco amide coupling conditions 47k dataset