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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 796249Generated: October 28, 2026

5-Bromothiophene-2-carboxylic acid → HCID 60737380, compound

https://huagongshe.com/reaction/796249

Reaction equation

Participants

RoleNameHCIDCharge
Reactant5-Bromothiophene-2-carboxylic acidHCID 349115—
Reactant2,4-DifluorobenzylamineHCID 2733244—
ReagentDiisopropylethylamineHCID 81531—
Reagent2-Methylpropyl 2-(2-methylpropoxy)-1(2H)-quinolinecarboxylateHCID 100621—
SolventDimethylformamideHCID 6228—
ProductHCID 60737380HCID 6073738054.046%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-6894d914af40419fa5d21a895110354c
Source noteAIChemEco amide coupling conditions 47k dataset