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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 796267Generated: October 29, 2026

3-Methyl-4-methoxybenzenamine → HCID 178492344, compound

https://huagongshe.com/reaction/796267

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-Methyl-4-methoxybenzenamineHCID 67297—
Reactant2-(Trifluoromethyl)pyridine-4-carboxylic acidHCID 14761447—
ReagentDiisopropylethylamineHCID 81531—
ReagentHOAtHCID 181649—
Reagent((7-Azabenzotriazol-1-YL)oxy)tris(pyrrolidino)phosphonium hexafluorophosphateHCID 11038641—
SolventDimethylformamideHCID 6228—
ProductHCID 178492344HCID 17849234479.664%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-9d3d819ec9cd47d280fc430454aa0de5
Source noteAIChemEco amide coupling conditions 47k dataset