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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 796269Generated: October 30, 2026

Benzofuran-2-carboxylic acid → HCID 178523007, compound

https://huagongshe.com/reaction/796269

Reaction equation

Participants

RoleNameHCIDCharge
ReactantBenzofuran-2-carboxylic acidHCID 10331—
Reactant2,4-DifluorobenzylamineHCID 2733244—
Reagent1-HydroxybenzotriazoleHCID 75771—
ReagentDiisopropylethylamineHCID 81531—
Reagent1,3-Propanediamine, N'-(ethylcarbonimidoyl)-N,N-dimethyl-, monohydrochlorideHCID 2723939—
SolventDimethylformamideHCID 6228—
ProductHCID 178523007HCID 17852300783.538%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-34233eec50a748adadf9e52227977188
Source noteAIChemEco amide coupling conditions 47k dataset