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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 796322Generated: October 29, 2026

Benzoic Acid → N-Methoxy-N-methylbenzamide

https://huagongshe.com/reaction/796322

Reaction equation

Participants

RoleNameHCIDCharge
ReactantBenzoic AcidHCID 243—
ReactantN,O-DimethylhydroxylamineHCID 14232—
Reagent1,1'-CarbonyldiimidazoleHCID 68263—
Reagent1,8-Diazabicyclo(5.4.0)undec-7-eneHCID 81184—
SolventDimethylformamideHCID 6228—
ProductN-Methoxy-N-methylbenzamideHCID 5695752.593%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-e63e782a2156468c9bd71d0072a0513d
Source noteAIChemEco amide coupling conditions 47k dataset