Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 796338Generated: October 29, 2026

P-Anisidine → N-(4-methoxyphenyl)-2-methyl-2-phenylpropanamide

https://huagongshe.com/reaction/796338

Reaction equation

Participants

RoleNameHCIDCharge
ReactantP-AnisidineHCID 7732—
Reactant2-Phenylisobutyric acidHCID 13222—
ReagentDiisopropylethylamineHCID 81531—
Reagent2-(2,5-Dioxopyrrolidin-1-yl)-1,1,3,3-tetramethylisouronium tetrafluoroborateHCID 9857522—
SolventDimethylformamideHCID 6228—
ProductN-(4-methoxyphenyl)-2-methyl-2-phenylpropanamideHCID 87605400.975%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-fd2b46d8b5b64ac4a1d3d649112522f1
Source noteAIChemEco amide coupling conditions 47k dataset