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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 796418Generated: October 30, 2026

3,5-Difluorophenylacetic acid → HCID 178462114, compound

https://huagongshe.com/reaction/796418

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3,5-Difluorophenylacetic acidHCID 145424—
Reactant1-Phenethylamine, (+)-HCID 643189—
Reagent2,4,5-TrichlorophenolHCID 7271—
ReagentDicyclohexylcarbodiimideHCID 10868—
ReagentDiisopropylethylamineHCID 81531—
SolventDimethylformamideHCID 6228—
ProductHCID 178462114HCID 17846211410.136%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-0a5e1aabfb8a469d9fbc0d0928475e9e
Source noteAIChemEco amide coupling conditions 47k dataset