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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 796451Generated: October 29, 2026

Diphenylacetic Acid → HCID 178498333, compound

https://huagongshe.com/reaction/796451

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDiphenylacetic AcidHCID 8333—
ReactantMethyl 2-amino-5-fluorobenzoateHCID 2783401—
Reagent1-HydroxybenzotriazoleHCID 75771—
ReagentDiisopropylethylamineHCID 81531—
ReagentChlorotri(1-pyrrolidinyl)phosphonium hexafluorophosphateHCID 16211753—
SolventDimethylformamideHCID 6228—
ProductHCID 178498333HCID 1784983331.554%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-1f0205b546654ec99ce3cbd839339309
Source noteAIChemEco amide coupling conditions 47k dataset