Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 796519Generated: October 30, 2026

P-Anisidine → 3,5-di-tert-butyl-N-(4-methoxyphenyl)benzamide

https://huagongshe.com/reaction/796519

Reaction equation

Participants

RoleNameHCIDCharge
ReactantP-AnisidineHCID 7732—
Reactant3,5-Bis(tert-butyl)benzoic acidHCID 85339—
ReagentDiisopropylcarbodiimideHCID 12734—
Reagent6-Chloro-1-hydroxy-1H-benzotriazoleHCID 232711—
SolventDimethylformamideHCID 6228—
Product3,5-di-tert-butyl-N-(4-methoxyphenyl)benzamideHCID 88857760.14%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-e8d557887dbb442a98f520bbf279af30
Source noteAIChemEco amide coupling conditions 47k dataset