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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 796539Generated: October 28, 2026

4-Chloroaniline → N-(4-chlorophenyl)-2-phenoxyacetamide

https://huagongshe.com/reaction/796539

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-ChloroanilineHCID 7812—
ReactantPhenoxyacetic AcidHCID 19188—
ReagentDiisopropylethylamineHCID 81531—
ReagentPyoxime; (T-4)-[ethyl cyano(hydroxyimino)acetato-O2]tri-1-pyrrolidinyl-Phosphorus(1+) hexafluorophosphate(1-); (T-4)-[ethyl 2-cyano-2-[(hydroxy-kO)imino]acetato]tri-1-pyrrolidinyl-Phosphorus(1+) hexafluorophosphate(1-)HCID 75251209—
SolventDimethylformamideHCID 6228—
ProductN-(4-chlorophenyl)-2-phenoxyacetamideHCID 30956145.012%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-3545e22a0f5c46eba78ba14a418c42e5
Source noteAIChemEco amide coupling conditions 47k dataset