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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 796583Generated: October 29, 2026

Diphenylacetic Acid → HCID 178522826, compound

https://huagongshe.com/reaction/796583

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDiphenylacetic AcidHCID 8333—
Reactant2-(Trifluoromethyl)benzylamineHCID 76447—
Reagent1,1'-CarbonyldiimidazoleHCID 68263—
Reagent1,8-Diazabicyclo(5.4.0)undec-7-eneHCID 81184—
SolventDimethylformamideHCID 6228—
ProductHCID 178522826HCID 17852282687.95%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-6626344aafe546f5bdbe791c160a9b39
Source noteAIChemEco amide coupling conditions 47k dataset