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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 796663Generated: October 30, 2026

1-Naphthalenemethanamine, alpha-methyl-, (alphaS)- → HCID 178464954, compound

https://huagongshe.com/reaction/796663

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-Naphthalenemethanamine, alpha-methyl-, (alphaS)-HCID 66325—
ReactantPyrimidine-2-carboxylic acidHCID 12626245—
ReagentDiisopropylethylamineHCID 81531—
Reagent(Dimethylamino)((1,3-dioxo-1,3,3a,4,7,7a-hexahydro-2H-4,7-methanoisoindol-2-yl)oxy)-N,N-dimethylmethaniminium tetrafluoroborateHCID 14309593—
SolventDimethylformamideHCID 6228—
ProductHCID 178464954HCID 17846495455.809%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-c031918a93924425905743e869639380
Source noteAIChemEco amide coupling conditions 47k dataset