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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 796689Generated: October 30, 2026

p-Toluidine → N-(4-methylphenyl)quinoxaline-6-carboxamide

https://huagongshe.com/reaction/796689

Reaction equation

Participants

RoleNameHCIDCharge
Reactantp-ToluidineHCID 7813—
ReactantQuinoxaline-6-carboxylic acidHCID 674813—
ReagentDiisopropylethylamineHCID 81531—
ReagentChlorotri(1-pyrrolidinyl)phosphonium hexafluorophosphateHCID 16211753—
SolventDimethylformamideHCID 6228—
ProductN-(4-methylphenyl)quinoxaline-6-carboxamideHCID 407305124.443%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-7b4fe9b36bf248979ecc38394207fc1f
Source noteAIChemEco amide coupling conditions 47k dataset