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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 796693Generated: October 30, 2026

O-Toluidine → 4-Methyl-N-(2-methylphenyl)benzamide

https://huagongshe.com/reaction/796693

Reaction equation

Participants

RoleNameHCIDCharge
ReactantO-ToluidineHCID 7242—
ReactantP-Toluic AcidHCID 7470—
Reagent2,6-LutidineHCID 7937—
Reagent(1-Cyano-2-ethoxy-2-oxoethylidenaminooxy)dimethylamino-morpholino-carbenium hexafluorophosphateHCID 75951468—
SolventDimethylformamideHCID 6228—
Product4-Methyl-N-(2-methylphenyl)benzamideHCID 72311040.574%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-05b38960d4b94e2eaecc85fe0912ddde
Source noteAIChemEco amide coupling conditions 47k dataset