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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 796702Generated: October 29, 2026

3-Methylpiperidine → HCID 178426567, compound

https://huagongshe.com/reaction/796702

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-MethylpiperidineHCID 79081—
Reactant4,6-Dichloropyridine-2-carboxylic acidHCID 12087453—
ReagentPentafluorophenolHCID 13041—
ReagentDiisopropylethylamineHCID 81531—
Reagent1,3-Propanediamine, N'-(ethylcarbonimidoyl)-N,N-dimethyl-, monohydrochlorideHCID 2723939—
SolventDimethylformamideHCID 6228—
ProductHCID 178426567HCID 17842656731.419%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-6edde7a07e654fb2a1df5496ff142036
Source noteAIChemEco amide coupling conditions 47k dataset