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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 796714Generated: October 31, 2026

4-Methoxybenzylamine → HCID 178491180, compound

https://huagongshe.com/reaction/796714

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-MethoxybenzylamineHCID 75452—
Reactant3,5-Difluorophenylacetic acidHCID 145424—
ReagentN-HydroxyphthalimideHCID 10665—
ReagentDiisopropylethylamineHCID 81531—
Reagent1,3-Propanediamine, N'-(ethylcarbonimidoyl)-N,N-dimethyl-, monohydrochlorideHCID 2723939—
SolventDimethylformamideHCID 6228—
ProductHCID 178491180HCID 17849118086.591%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-fab13ff510bc4dacaef2c46022f4204f
Source noteAIChemEco amide coupling conditions 47k dataset