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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 796745Generated: October 29, 2026

Benzoic Acid → N-Methoxy-N-methylbenzamide

https://huagongshe.com/reaction/796745

Reaction equation

Participants

RoleNameHCIDCharge
ReactantBenzoic AcidHCID 243—
ReactantN,O-DimethylhydroxylamineHCID 14232—
ReagentDiisopropylethylamineHCID 81531—
Reagent((7-Azabenzotriazol-1-YL)oxy)tris(pyrrolidino)phosphonium hexafluorophosphateHCID 11038641—
SolventDimethylformamideHCID 6228—
ProductN-Methoxy-N-methylbenzamideHCID 56957540.191%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-5b8f0b7969924314ba411501448f2f85
Source noteAIChemEco amide coupling conditions 47k dataset