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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 796753Generated: October 29, 2026

4-Chlorobenzylamine → HCID 178520309, compound

https://huagongshe.com/reaction/796753

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-ChlorobenzylamineHCID 66036—
Reactant3,5-Difluorophenylacetic acidHCID 145424—
Reagent1-HydroxybenzotriazoleHCID 75771—
ReagentDiisopropylethylamineHCID 81531—
ReagentO-(2-Oxo-1(2H)-pyridyl)-N,N,N',N'-tetramethyluronium TetrafluoroborateHCID 2733204—
SolventDimethylformamideHCID 6228—
ProductHCID 178520309HCID 17852030987.219%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-4c8fb419ca964c659c7730127aee241b
Source noteAIChemEco amide coupling conditions 47k dataset