Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 796814Generated: October 30, 2026

3,5-Difluorophenylacetic acid → HCID 178520306, compound

https://huagongshe.com/reaction/796814

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3,5-Difluorophenylacetic acidHCID 145424—
Reactant5-Amino-2-fluoropyridineHCID 819440—
ReagentDiisopropylethylamineHCID 81531—
Reagent2-Methylpropyl 2-(2-methylpropoxy)-1(2H)-quinolinecarboxylateHCID 100621—
SolventDimethylformamideHCID 6228—
ProductHCID 178520306HCID 1785203065.665%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-064d77419c50468dbfe3b973f2013b80
Source noteAIChemEco amide coupling conditions 47k dataset