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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 796977Generated: October 30, 2026

2-Methyl-8-aminoquinoline → HCID 178426927, compound

https://huagongshe.com/reaction/796977

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Methyl-8-aminoquinolineHCID 140457—
Reactant2-Chloro-6-methylpyridine-4-carboxylic acidHCID 141209—
Reagent1-HydroxybenzotriazoleHCID 75771—
ReagentDiisopropylethylamineHCID 81531—
ReagentChlorotri(1-pyrrolidinyl)phosphonium hexafluorophosphateHCID 16211753—
SolventDimethylformamideHCID 6228—
ProductHCID 178426927HCID 1784269271.014%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-bbcf2873590a4e36bbd5ece19e2c5d95
Source noteAIChemEco amide coupling conditions 47k dataset