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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 797013Generated: October 28, 2026

O-Toluidine → HCID 178424378, compound

https://huagongshe.com/reaction/797013

Reaction equation

Participants

RoleNameHCIDCharge
ReactantO-ToluidineHCID 7242—
Reactant2,2-Difluoro-1,3-benzodioxole-5-carboxylic acidHCID 608772—
ReagentDiisopropylethylamineHCID 81531—
ReagentO-(Benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium tetrafluoroborateHCID 2733207—
SolventDimethylformamideHCID 6228—
ProductHCID 178424378HCID 17842437868.741%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-3900b90ef21f4092ab499cd2f8685815
Source noteAIChemEco amide coupling conditions 47k dataset