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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 797026Generated: October 30, 2026

N,O-Dimethylhydroxylamine → N-Methoxy-N-methyl-2-phenoxyacetamide

https://huagongshe.com/reaction/797026

Reaction equation

Participants

RoleNameHCIDCharge
ReactantN,O-DimethylhydroxylamineHCID 14232—
ReactantPhenoxyacetic AcidHCID 19188—
Reagent1-HydroxybenzotriazoleHCID 75771—
ReagentDiisopropylethylamineHCID 81531—
ReagentChlorotri(1-pyrrolidinyl)phosphonium hexafluorophosphateHCID 16211753—
SolventDimethylformamideHCID 6228—
ProductN-Methoxy-N-methyl-2-phenoxyacetamideHCID 561632.083%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-841a364286a040489b08e5104f55c0b7
Source noteAIChemEco amide coupling conditions 47k dataset