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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 7972Generated: October 25, 2026

2-isobutyl-6-(2,4-difluorophenyl)-4-phthalimidomethyl-2H-pyridazin-3-one → 4-aminomethyl-6-(2,4-difluorophenyl)-2-isobutyl-2H-pyridazin-3-one

https://huagongshe.com/reaction/7972

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-isobutyl-6-(2,4-difluorophenyl)-4-phthalimidomethyl-2H-pyridazin-3-oneHCID 21991587—
Reactant4-carboxy-6-(2,4-difluorophenyl)-2H-pyridazin-3-oneHCID 21991677—
Product4-aminomethyl-6-(2,4-difluorophenyl)-2-isobutyl-2H-pyridazin-3-oneHCID 21991522—

Reaction Steps

Following the procedure of Example 24 (2), 2-isobutyl-6-(2,4-difluorophenyl)-4-phthalimidomethyl-2H-pyridazin-3-one was reacted to yield the title compound as a slightly yellow oil (yield: 98.4%).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07087606B2
Source datasetuspto-grants-2006_08
ORD IDord-1fcb1e8a1161461b9c33d7d322bdcc0b
Source noteuspto-grants-2006_08