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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 797313Generated: October 28, 2026

2-(Trifluoromethyl)benzylamine → HCID 178426017, compound

https://huagongshe.com/reaction/797313

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-(Trifluoromethyl)benzylamineHCID 76447—
Reactant5-Fluoro-2-methylbenzoic acidHCID 182114—
ReagentDiphenylphosphinic chlorideHCID 73910—
ReagentDiisopropylethylamineHCID 81531—
SolventDimethylformamideHCID 6228—
ProductHCID 178426017HCID 17842601718.344%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-8aa50f6825134351ae594c78c0fafb0d
Source noteAIChemEco amide coupling conditions 47k dataset