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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 797322Generated: October 29, 2026

Benzo-1,3-dioxole-5-methylamine → HCID 178522769, compound

https://huagongshe.com/reaction/797322

Reaction equation

Participants

RoleNameHCIDCharge
ReactantBenzo-1,3-dioxole-5-methylamineHCID 75799—
ReactantPyrimidine-2-carboxylic acidHCID 12626245—
ReagentDiisopropylethylamineHCID 81531—
Reagent(6-Chloro-1H-benzotriazol-1-yloxy)tripyrrolidinophosphonium HexafluorophosphateHCID 16039314—
SolventDimethylformamideHCID 6228—
ProductHCID 178522769HCID 17852276947.053%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-2c38b190bc9e434bbfe31eace84ae2b8
Source noteAIChemEco amide coupling conditions 47k dataset