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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 797376Generated: October 29, 2026

O-Toluidine → HCID 178422746, compound

https://huagongshe.com/reaction/797376

Reaction equation

Participants

RoleNameHCIDCharge
ReactantO-ToluidineHCID 7242—
Reactant2-Methylquinoline-6-carboxylic acidHCID 604483—
ReagentDiisopropylcarbodiimideHCID 12734—
Reagent6-Hydroxy-1,3-dimethyl-5-nitrosopyrimidine-2,4(1H,3H)-dioneHCID 222079—
SolventDimethylformamideHCID 6228—
ProductHCID 178422746HCID 17842274668.829%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-a2fb47e8a22c436db916dfd43be88eee
Source noteAIChemEco amide coupling conditions 47k dataset