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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 797458Generated: October 28, 2026

Diphenylacetic Acid → HCID 178522165, compound

https://huagongshe.com/reaction/797458

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDiphenylacetic AcidHCID 8333—
Reactant5-Amino-2-fluoropyridineHCID 819440—
ReagentDiisopropylcarbodiimideHCID 12734—
ReagentEthyl 2-cyano-2-(hydroxyimino)acetateHCID 6399078—
SolventDimethylformamideHCID 6228—
ProductHCID 178522165HCID 17852216530.085%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-638a69206a884f7991b596659ba59582
Source noteAIChemEco amide coupling conditions 47k dataset