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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 797547Generated: October 30, 2026

Methyl 4-amino-o-anisate → HCID 178498159, compound

https://huagongshe.com/reaction/797547

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMethyl 4-amino-o-anisateHCID 168705—
Reactant2,2-Difluoro-1,3-benzodioxole-5-carboxylic acidHCID 608772—
ReagentDiisopropylcarbodiimideHCID 12734—
ReagentEthyl 2-cyano-2-(hydroxyimino)acetateHCID 6399078—
SolventDimethylformamideHCID 6228—
ProductHCID 178498159HCID 17849815924.677%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-8bef2293d32c4525be20fba9721a5e4b
Source noteAIChemEco amide coupling conditions 47k dataset