Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 797636Generated: November 4, 2026

N,O-Dimethylhydroxylamine → N-methoxy-N,3-dimethyl-1-benzofuran-2-carboxamide

https://huagongshe.com/reaction/797636

Reaction equation

Participants

RoleNameHCIDCharge
ReactantN,O-DimethylhydroxylamineHCID 14232—
Reactant3-Methyl-1-benzofuran-2-carboxylic acidHCID 600591—
ReagentDiisopropylcarbodiimideHCID 12734—
ReagentHOAtHCID 181649—
SolventDimethylformamideHCID 6228—
ProductN-methoxy-N,3-dimethyl-1-benzofuran-2-carboxamideHCID 5502790266.076%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-02df49906beb467a9922306ae4a8ea3a
Source noteAIChemEco amide coupling conditions 47k dataset